Habib Olapade

Botulism

Botulism

Botulism is a paralytic disease caused by botulism toxin, which is produced by C botulinum, an anaerobic spore-forming bacillus found in soil. Four toxin types – F, E, B, and A cause disease in humans. Naturally occurring botulism comes in three forms: wound botulism, infant botulism, and food borne botulism. Food borne botulism is caused by ingestion of preformed toxin present in vacuum packed, canned, or smoked foods. Infant and wound botulism are both caused by the presence of organisms in the gut or wound that secrete toxins. Symptoms include diplopia and loss of accommodation, fixed dilated pupils, cranial never palsies with extraocular muscle impairment, dry mouth, dysphonia, dysphagia, and ptosis. Paralysis that develops into respiratory failure and death may occur unless assistance is provided. To test for the disease, the practitioner should use mouse inoculation and specific antiserum. If the practitioner suspects that her patient is suffering from botulism, she should contact State health authorities or the |Centers for Disease Control for assistance in procuring the equine serum heptavalent botulism antitoxin and the assays for toxin in serum, stool, or food. Skin testing is also recommended to remove hypersensitivity to the antitoxin preparation. Antitoxin should be administered within twenty-four hours of the onset of symptoms and parenteral fluids should be provided while the patient has difficulty swallowing. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Duration: 4 min

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